Buffalo Bills fans, let’s make Billy the Buffalo proud. We’ve got the latest Bills betting odds, futures odds, and season win total odds. Next, we included a quick primer on how to bet on the Buffalo Bills. Combine moneyline bets with your own NFL handicapping to get an edge.
We also have Buffalo’s recent standings, odds to make the playoffs, odds to win the most regular season games, and this season’s schedule and results. Use this information to help you make informed wagers when the Buffalo Bills face key opponents this season.
Table of Contents
- Betting Sites
- Game Odds
- Prop Bets
- Win Total Odds
- Odds to Make Playoffs
- Super Bowl Odds
- Conference Odds
- Division Odds
- To Win Most Games
- Matchup Results
- Standings
Best Buffalo Bills Sports Betting Sites
| Bonus | |
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Buffalo Bills Game Odds
Point spread, total, and moneyline odds for Buffalo Bills matchups from licensed and regulated US sports betting sites. We explain how to place each bet below.
Markets| Game |
 BetMGMBet |
 BetRiversBet |
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Buffalo Bills Prop Bets
Review prop bets for the next Buffalo Bills matchup. Will a safety be scored? Will the game go to overtime? How will the quarterback and kicker perform? Will the Bills team point total be over or under the sportsbook’s line?
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BetMGM Bet |
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Ravens
Bills
9/07/25 7:20pm CDT
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Pending BetMGM |
Buffalo Bills Win Total Odds
The season win total is part prop, part future hybrid. The plus and minus values assign odds to either side of the team’s win total line. This bet functions like a total bet. Bet either over or under the sportsbook’s line.
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BetMGM Bet |
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Bills
2025-26 Season Win Total
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Buffalo Bills Odds to Make Playoffs
Bet “Yes” if you think a team will make the playoffs this season, or “No” if you think they won’t. Like the season win total, this bet is part prop, part future. With futures, you can only bet on the Buffalo Bills to win a particular event. But with the odds to make the playoffs bet, you can bet either “Yes” or “No” on the Buffalo Bills to make the playoffs.
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BetMGM Bet |
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Bills
2024-25 To Make Playoffs
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Buffalo Bills Super Bowl Odds
Here are the Bills’ odds to win the Super Bowl. SportsBetting3.com how to place futures bets with our helpful tutorial.
| Team |
BetMGM |
|---|---|
| Bills | +750 Bet |
Buffalo Bills Odds to win the AFC
Review the Buffalo Bills’ odds to win the AFC. Conference futures odds update 2-3 times per week throughout the season.
| Team |
BetMGM |
BetRivers |
|---|---|---|
| Bills | +375 Bet |
+400 Bet |
Buffalo Bills Odds to win the AFC East
Here are the Buffalo Bills’ odds to win the AFC East. Like the conference futures, odds to win each division update 2-3 times per week throughout the season.
| Team |
BetRivers |
|---|---|
| Bills | -265 Bet |
Buffalo Bills Odds to win the Most Regular Season Games
Bet on Buffalo if you think the Bills will win the most regular season games. This bet requires a team to win more games than any other, with any ties broken by the sportsbook’s wagering rules. If you think Buffalo can win at least half their games, then they would be in the running to win the most regular season games. Unlike other futures bets for a particular event, this bet is based on a team’s performance relative to others over the course of the regular season.
| Team |
BetMGM |
|---|---|
| Bills | +450 Bet |
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Buffalo Bills Schedule and Results
Review the Bills’ recent schedule and game results from the preseason, regular season, and postseason. Be sure to check out your sportsbook’s NFL promotions during the postseason. Many sports betting sites will offer bonus codes for teams that make the playoffs.
2025-26 Buffalo Bills Games & Results
| Week | Matchup | Date & Result |
|---|---|---|
| Preseason 1 | Giants vs Bills |
Saturday, August 9th, 2025 12:00 pm CDT |
| Preseason 2 | Bills vs Bears |
Sunday, August 17th, 2025 7:00 pm CDT |
| Preseason 3 | Bills vs Buccaneers |
Saturday, August 23rd, 2025 6:30 pm CDT |
| Week 1 | Ravens vs Bills |
Sunday, September 7th, 2025 7:20 pm CDT |
| Week 2 | Bills vs Jets |
Sunday, September 14th, 2025 12:00 pm CDT |
| Week 3 | Dolphins vs Bills |
Thursday, September 18th, 2025 7:15 pm CDT |
| Week 4 | Saints vs Bills |
Sunday, September 28th, 2025 12:00 pm CDT |
| Week 5 | Patriots vs Bills |
Sunday, October 5th, 2025 7:20 pm CDT |
| Week 6 | Bills vs Falcons |
Monday, October 13th, 2025 6:15 pm CDT |
| Week 7 | Bills Bye Week |
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| Week 8 | Bills vs Panthers |
Sunday, October 26th, 2025 12:00 pm CDT |
| Week 9 | Chiefs vs Bills |
Sunday, November 2nd, 2025 3:25 pm CST |
| Week 10 | Bills vs Dolphins |
Sunday, November 9th, 2025 12:00 pm CST |
| Week 11 | Buccaneers vs Bills |
Sunday, November 16th, 2025 12:00 pm CST |
| Week 12 | Bills vs Texans |
Thursday, November 20th, 2025 7:15 pm CST |
| Week 13 | Bills vs Steelers |
Sunday, November 30th, 2025 3:25 pm CST |
| Week 14 | Bengals vs Bills |
Sunday, December 7th, 2025 3:25 pm CST |
| Week 15 | Bills vs Patriots |
Sunday, December 14th, 2025 12:00 pm CST |
| Week 16 | Bills vs Browns |
Sunday, December 21st, 2025 12:00 pm CST |
| Week 17 | Eagles vs Bills |
Sunday, December 28th, 2025 3:25 pm CST |
| Week 18 | Jets vs Bills |
Saturday, January 3rd, 2026 11:00 pm CST |
How to Bet on the Buffalo Bills
Time needed: 2 minutes.
How to Bet on the Buffalo Bills
- Open a new sports betting .
Review our list of NFL betting sites. Each sportsbook offers many ways to bet on the Buffalo Bills. Make sure to enter all your personal details correctly. Don't forget to add your bonus code.
- Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Paypal.
- Tap to the sportsbook's NFL page, look for the Buffalo Bills.
Navigate to the sportsbook's NFL page. Next, look for live or Buffalo Bills matchups. Review any Buffalo Bills futures odds.
- Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your balance after the Buffalo Bills bet has been graded.
Point Spread Bets
The Buffalo Bills will be favorites when their point spread line has a minus sign “-” before the number. They’ll be underdogs when the line has a plus sign “+” before the number.
The odds follow the point spread line. Standard betting odds are -110. That means you’ll risk $110 to win $100. Sometimes, the odds might be higher or lower depending on the betting action for or against the Bills.
Moneyline Bets
Pick either the favorite or the underdog team to win. Unlike the point spread, you’re simply picking the outright winner.
Moneyline favorites have a minus sign “-” before their number. This number indicates how much you risk to win $100. For example, if the Bills are -250 favorites, you would risk $250 to win $100.
Moneyline underdogs have a plus sign “+” before their number. This number indicates how much you win if you risk $100. If Buffalo is a +300 underdog, you would risk $100 to win $300.
Betting an obvious favorite to win isn’t always a good idea, even if it’s for the Bills to win the game. Betting big moneyline favorites means you tie up a large amount of bankroll for a small profit. Sometimes it’s more economical to bet the point spread instead.
Total Bets
Decide whether the sum of both teams’ final scores will be over or under the sportsbook’s total line.
Each side will have its own odds. Occasionally, both sides will have -110 standard odds. Over will be abbreviated as “o” and under will be abbreviated as “u”. Look for each side’s odds to the right of each letter.
With total bets, you have to consider ability of the Bills and their opponent to put points on the board. Carefully determine whether the game will be a shootout between two high powered offenses, or a grind between two defensive Bills. High-scoring games typically will get higher total lines and more expensive over odds compared to lower-scoring games, which will get lower total lines and less expensive under odds.
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Buffalo Bills Standings
Review the Buffalo Bills’ current season standings, or have a look at standings from previous years. Current streak and L5 game records can be especially helpful when sizing up a bet. A team’s recent performance is a better indicator of its ability to win games compared to its overall season standing.
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| xz - Buffalo Bills | 13 | 4 | 0 | 0.765 | 525 | 368 | 8-0-0 | 5-4-0 | 5-1-0 | 0.833 | 9-3-0 | 0.750 | 1L | 3-2-0 |
FAQs on the Buffalo Bills
The Buffalo Bills have a 11.5 game win total line at BetMGM, with the Over -160 and the Under +135. Betting "Over" means you risk $160 to win $100, while a bet on the "Under" means you risk $100 to win $135.
The Buffalo Bills have +475 odds to not make the 2024-25 playoffs. Betting "No" means a winning $100 bet would pay $475.
As of Wednesday, May 21st, 2025, the Buffalo Bills have +750 odds to win Super Bowl 60 at BetMGM. That means a $100 bet would pay $750. The implied probability for the Buffalo Bills to win the Super Bowl is 11.76%.
As of Wednesday, May 21st, 2025, the Buffalo Bills have +375 odds to win the 2025-26 AFC. You would risk $100 to win $375 on the Bills to win the AFC at BetMGM. The implied probability for the Buffalo Bills to win their conference is 21.05%.
As of Wednesday, May 21st, 2025, the Buffalo Bills have -265 odds to win the 2025-26 AFC East at BetRivers. That means you risk $265 to win $100. The implied probability for the Buffalo Bills to win their division is 72.6%.
Betting Odds for Other NFL Teams
- Arizona Cardinals Betting Odds
- Atlanta Falcons Betting Odds
- Baltimore Ravens Betting Odds
- Buffalo Bills Betting Odds
- Carolina Panthers Betting Odds
- Chicago Bears Betting Odds
- Cincinnati Bengals Betting Odds
- Cleveland Browns Betting Odds
- Dallas Cowboys Betting Odds
- Denver Broncos Betting Odds
- Detroit Lions Betting Odds
- Green Bay Packers Betting Odds
- Houston Texans Betting Odds
- Indianapolis Colts Betting Odds
- Jacksonville Jaguars Betting Odds
- Kansas City Chiefs Betting Odds
- Las Vegas Raiders Betting Odds
- Los Angeles Chargers Betting Odds
- Los Angeles Rams Betting Odds
- Miami Dolphins Betting Odds
- Minnesota Vikings Betting Odds
- New England Patriots Betting Odds
- New Orleans Saints Betting Odds
- New York Giants Betting Odds
- New York Jets Betting Odds
- Philadelphia Eagles Betting Odds
- Pittsburgh Steelers Betting Odds
- San Francisco 49ers Betting Odds
- Seattle Seahawks Betting Odds
- Tampa Bay Buccaneers Betting Odds
- Tennessee Titans Betting Odds
- Washington Commanders Betting Odds
NFL Betting Resources
- How to Bet on the NFL – An in-depth look at how to place bets on the NFL, including common straight bets and exotics like parlays, teasers, and props.
- NFL Betting Sites – Our list of the best NFL betting sites features licensed and legal US sportsbooks, just in time for the action on the gridiron.
- NFL Betting Odds – Current NFL odds for matchups, including the preseason and postseason. Review futures odds, the greatest all-time teams, regular-season standings, and valuable handicapping strategies.
- NFL Prop Bets – Prop bets from NFL matchups, including a complete NFL prop betting tutorial. Learn how to bet on NFL props.
- NFL Futures Odds – Odds for popular NFL Futures, like the Super Bowl, AFC and NFC conference winners, each division winner, and offensive and defensive player awards. Learn how to bet on NFL futures in minutes.
- NFL Win Total Odds – Review regular season win total lines and odds for each team. to place you bet before each team’s first game of the regular season.
- NFL Game to Overtime Prop Bet – See odds for games, then review overtime game counts from recent seasons.
- NFL Safety to be Scored Prop Bet – Review odds of a safety happening in games, then bet “Yes” or “No”.
- NFL First Team to Score Prop Bet – See odds for which team will score first, then learn how to bet on this prop.
- Undefeated NFL Teams – See which teams are still undefeated in the current regular season.
- NFL Biggest Rivalries – Review the NFL’s biggest rivalries by division, catching up on each rivalry’s history and recent matchup results.
- Super Bowl Betting – The latest Super Bowl odds for every NFL team, plus a great guide to how to bet on the Super Bowl. Review how to bet Super Bowl props and recent winning teams.
- Super Bowl Betting Bonuses – See our curated list of betting bonuses just in time for this season’s big game.
- Quarterback Props – Review each quarterback’s regular season performance props. Bet over or under the sportsbook’s line.
- Running Back Props – See performance props for the league’s top running backs. Bet over or under the sportsbook’s line.
- Receiver Props – Have a look at regular season performance lines for receiving yards and receiving touchdowns, then bet over or under the sportsbook’s line.
- How to Read NFL Odds – Great for beginners: learn what the numbers for each bet mean.
- NFL Team Betting Odds – Betting odds and bonuses for each NFL team, including their Super Bowl, Conference, and Division futures, plus historical standings going back to before you were born.