The Orioles will play the Red Sox on Thursday, May 22nd, 2025. Your timezone's first pitch time is 5:45 pm CDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Baltimore Orioles have a 84.67 power ranking. The power ranking for the Boston Red Sox is 92.00.
- Visiting Baltimore Orioles - The Baltimore Orioles have a 8-17 record as a visiting team, ranking them 9th Overall for visiting team wins.
- Home Boston Red Sox - The Boston Red Sox have a 14-11 record as a home team. They rank 5th for home team wins in the Overall standings.
- Runs Scored - The Baltimore Orioles currently stand 22nd (183) Overall, with the Boston Red Sox ranking 7th (239) for runs scored.
- Runs Allowed - The Baltimore Orioles are 4th (268) Overall for runs allowed. The Boston Red Sox stand 8th (227) for runs allowed.
- Team Streaks - The Baltimore Orioles won their last game. Meanwhile, the Boston Red Sox have won their last 2 games.
- Team Records - The Baltimore Orioles have a 16-32 Overall record (13.0 GB American East Division), with the Boston Red Sox possessing a 25-25 Overall standing (5.5 GB American East Division).
Captain Shady Lines
A broken com is right at least twice a day.

Avast ye scallywags! The Orioles be sailing to Boston with a pitiful record...
Aye, with a win percentage of only 0.333, the Orioles be sinking fast...
Ye best be heading to SportsBetting3.com to bet on this game... (review the odds below)
The Red Sox be looking to plunder another victory at Fenway Park...
But don't count out the Orioles just yet, they may surprise ye...
So gather yer crew and tune in to watch this battle on the high seas!
Best Orioles at Red Sox Odds
Underdog Baltimore Orioles |
Favorite Boston Red Sox |
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Over | Under |
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Underdog Baltimore Orioles |
Favorite Boston Red Sox |
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Matchup Odds FAQs
The Boston Red Sox are the -125 moneyline favorite at BetRivers and the Baltimore Orioles are the +110 moneyline underdog at BetMGM.
The best over line is 8 -114 runs at BetRivers, which means you risk $114 to win $100 betting the over. The best under line is 8 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.
The Boston Red Sox are -1.5 +165 run line favorites at BetMGM, while the Baltimore Orioles are +1.5 -200 run line underdogs at BetMGM.
MLB Odds Example
Game |
![]() Bet |
---|---|
Orioles
Red Sox
5:45pm CDT
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+110-130 |
- Baltimore Orioles bettors risk $100 to win $110 at +110 odds. The implied probability for Baltimore Orioles is 47.62%.
- Boston Red Sox bettors risk $100 to win $76.92 at -130 odds. The implied probability for Boston Red Sox is 56.52%.
Baltimore Orioles at Boston Red Sox Prop Bets
![]() Bet |
|
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Orioles
Red Sox
First Team to Score
5:45pm CDT
|
-150+118Bet |
Orioles
Red Sox
Tie
1st Inning Winner
5:45pm CDT
|
+300+310-145Bet |
Orioles
Red Sox
Tie
First 3 Innings Winner
5:45pm CDT
|
+145+140+270Bet |
Orioles
Red Sox
To Extra Innings
5:45pm CDT
|
Yes +725No -1200Bet |
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|
Orioles
Red Sox
1st Team to Score Will Win
5:45pm CDT
|
Yes -250No +190Bet |
Orioles
Total Runs
BAL at BOS 5:45pm CDT |
3.5 o -1403.5 u +105Bet |
Red Sox
Total Runs
BAL at BOS 5:45pm CDT |
4.5 o +1154.5 u -150Bet |
Baltimore Orioles & Boston Red Sox Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Baltimore Orioles World Series Odds Team |
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Orioles | +10000 Bet |
+3500 Bet |
Team |
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Red Sox | +2500 Bet |
+2000 Bet |
Baltimore Orioles & Boston Red Sox Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
---|---|---|---|---|---|---|---|---|---|---|---|
Boston Red Sox | 25 | 25 | 0.500 | +8.0 | 14-11 | 11-14 | 239 | 227 | +12 | W2 | 5-5 |
Baltimore Orioles | 16 | 32 | 0.333 | +16.0 | 8-15 | 8-17 | 183 | 268 | -85 | W1 | 2-8 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Baltimore Orioles vs Boston Red Sox MLB Game
- Open a new sports betting before game time.
Review our list of sports betting sites. Open a new before the game starts on Thursday, May 22nd, 2025 at 5:45 pm CDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
- Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Paypal.
- Tap to the sportsbook's MLB page, look for the Baltimore Orioles vs Boston Red Sox Game.
Navigate to the sportsbook's MLB page. Next, look for live or matchups. Select the Baltimore Orioles vs Boston Red Sox Game.
- Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your balance after the game.
Other May 22, 2025 MLB Games
- Texas Rangers vs New York Yankees - 11:35am CDT
- San Diego Padres vs Toronto Blue Jays - 12:07pm CDT
- Philadelphia Phillies vs Colorado Rockies - 2:10pm CDT
- Los Angeles Angels vs Oakland Athletics - 2:35pm CDT
- Cleveland Guardians vs Detroit Tigers - 5:40pm CDT
- Milwaukee Brewers vs Pittsburgh Pirates - 5:40pm CDT
- Atlanta Braves vs Washington Nationals - 5:45pm CDT
- Seattle Mariners vs Houston Astros - 7:10pm CDT