Baltimore Orioles vs Boston Red Sox Odds

The Orioles will play the Red Sox on Thursday, May 22nd, 2025. Your timezone's first pitch time is 5:45 pm CDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


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Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The Baltimore Orioles have a 84.67 power ranking. The power ranking for the Boston Red Sox is 92.00.
  • Visiting Baltimore Orioles - The Baltimore Orioles have a 8-17 record as a visiting team, ranking them 9th Overall for visiting team wins.
  • Home Boston Red Sox - The Boston Red Sox have a 14-11 record as a home team. They rank 5th for home team wins in the Overall standings.
  • Runs Scored - The Baltimore Orioles currently stand 22nd (183) Overall, with the Boston Red Sox ranking 7th (239) for runs scored.
  • Runs Allowed - The Baltimore Orioles are 4th (268) Overall for runs allowed. The Boston Red Sox stand 8th (227) for runs allowed.
  • Team Streaks - The Baltimore Orioles won their last game. Meanwhile, the Boston Red Sox have won their last 2 games.
  • Team Records - The Baltimore Orioles have a 16-32 Overall record (13.0 GB American East Division), with the Boston Red Sox possessing a 25-25 Overall standing (5.5 GB American East Division).

Captain Shady Lines

A broken com is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scallywags! The Orioles be sailing to Boston with a pitiful record...

Aye, with a win percentage of only 0.333, the Orioles be sinking fast...

Ye best be heading to SportsBetting3.com to bet on this game... (review the odds below)

The Red Sox be looking to plunder another victory at Fenway Park...

But don't count out the Orioles just yet, they may surprise ye...

So gather yer crew and tune in to watch this battle on the high seas!

Best Orioles at Red Sox Odds


Best Moneyline Betting Odds
Underdog

Baltimore Orioles
Favorite

Boston Red Sox
The Boston Red Sox are the -125 moneyline favorite. Risk $125 to win $100 on the Boston Red Sox at how to bet on money lines.

Best Total Betting Odds
Over Under
total bets.

Best Run Line Betting Odds
Underdog

Baltimore Orioles
Favorite

Boston Red Sox
The Boston Red Sox have a -1.5 +165 run line at how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the Baltimore Orioles vs Boston Red Sox MLB game on Thursday, May 22nd, 2025?

The Boston Red Sox are the -125 moneyline favorite at BetRivers and the Baltimore Orioles are the +110 moneyline underdog at BetMGM.

What is the over-under total line for the Baltimore Orioles vs Boston Red Sox MLB game on Thursday, May 22nd, 2025?

The best over line is 8 -114 runs at BetRivers, which means you risk $114 to win $100 betting the over. The best under line is 8 +100 runs at BetMGM, and that means you risk $100 to win $100 betting the under.

What is the run line for the Baltimore Orioles vs Boston Red Sox MLB game on Thursday, May 22nd, 2025?

The Boston Red Sox are -1.5 +165 run line favorites at BetMGM, while the Baltimore Orioles are +1.5 -200 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Orioles
Red Sox
5:45pm CDT
+110-130
Bet $100 at BetMGM Pennsylvania
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Possible Moneyline Outcomes
  • Baltimore Orioles bettors risk $100 to win $110 at +110 odds. The implied probability for Baltimore Orioles is 47.62%.
  • Boston Red Sox bettors risk $100 to win $76.92 at -130 odds. The implied probability for Boston Red Sox is 56.52%.

Baltimore Orioles at Boston Red Sox Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Orioles
Red Sox
First Team to Score
5:45pm CDT
-150+118Bet
Orioles
Red Sox
Tie
1st Inning Winner
5:45pm CDT
+300+310-145Bet
Orioles
Red Sox
Tie
First 3 Innings Winner
5:45pm CDT
+145+140+270Bet
Orioles
Red Sox
To Extra Innings
5:45pm CDT
Yes +725No -1200Bet
BetMGM Sports Betting BetMGM
Orioles
Red Sox
1st Team to Score Will Win
5:45pm CDT
Yes -250No +190Bet
Orioles
Total Runs
BAL at BOS
5:45pm CDT
3.5 o -1403.5 u +105Bet
Red Sox
Total Runs
BAL at BOS
5:45pm CDT
4.5 o +1154.5 u -150Bet

Baltimore Orioles & Boston Red Sox Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

Baltimore Orioles World Series Odds
2025 Baltimore Orioles World Series Odds

Team
BetMGM Sports Betting BetMGM BetRivers Sports Betting BetRivers
Orioles
+10000
Bet
+3500
Bet
Boston Red Sox World Series Odds
2025 Boston Red Sox World Series Odds

Team
BetMGM Sports Betting BetMGM BetRivers Sports Betting BetRivers
Red Sox
+2500
Bet
+2000
Bet

Baltimore Orioles & Boston Red Sox Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - Baltimore Orioles, Boston Red Sox
Team W L Pct GB Home Away RS RA Diff Strk L10
Boston Red Sox 25 25 0.500 +8.0 14-11 11-14 239 227 +12 W2 5-5
Baltimore Orioles 16 32 0.333 +16.0 8-15 8-17 183 268 -85 W1 2-8

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Baltimore Orioles vs Boston Red Sox MLB Game

  1. Open a new sports betting before game time.

    Review our list of sports betting sites. Open a new before the game starts on Thursday, May 22nd, 2025 at 5:45 pm CDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Paypal.

  3. Tap to the sportsbook's MLB page, look for the Baltimore Orioles vs Boston Red Sox Game.

    Navigate to the sportsbook's MLB page. Next, look for live or matchups. Select the Baltimore Orioles vs Boston Red Sox Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your balance after the game.

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