The Mariners will play the Astros on Thursday, May 22nd, 2025. Your timezone's first pitch time is 7:10 pm CDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Seattle Mariners have a 94.00 power ranking. The power ranking for the Houston Astros is 91.67.
- Visiting Seattle Mariners - The Seattle Mariners have a 15-9 record as a visiting team, ranking them 2nd Overall for visiting team wins.
- Home Houston Astros - The Houston Astros have a 15-9 record as a home team. They rank 4th for home team wins in the Overall standings.
- Runs Scored - The Seattle Mariners currently stand 11th (227) Overall, with the Houston Astros ranking 19th (195) for runs scored.
- Runs Allowed - The Seattle Mariners are 15th (200) Overall for runs allowed. The Houston Astros stand 22nd (179) for runs allowed.
- Team Streaks - The Seattle Mariners won their last game. Meanwhile, the Houston Astros have lost their last 2 games.
- Team Records - The Seattle Mariners have a 28-20 Overall record (0.0 GB American West Division), with the Houston Astros possessing a 25-24 Overall standing (3.5 GB American West Division).
Captain Shady Lines
A broken com is right at least twice a day.
Avast ye Mariners! On Thursday, May 22nd, ye face the Houston Astros...
Ye better be ready to plunder that win with a 0.583 win percentage...
If ye want to make some doubloons, go to SportsBetting3.com and bet on this game...
The Astros may be at home, but they only have a 0.510 win percentage...
Don't be a scurvy dog and miss out on the chance to win...
Review the odds below and set sail for victory, me hearties!
Best Mariners at Astros Odds
| Underdog Houston Astros |
Favorite Seattle Mariners |
|---|---|
| Over | Under |
|---|---|
| Underdog Houston Astros |
Favorite Seattle Mariners |
|---|---|
Matchup Odds FAQs
The Seattle Mariners are the -134 moneyline favorite at BetRivers and the Houston Astros are the +115 moneyline underdog at BetMGM.
The best over line is 8.5 -117 runs at BetRivers, which means you risk $117 to win $100 betting the over. The best under line is 8.5 -102 runs at BetMGM, and that means you risk $102 to win $100 betting the under.
The Seattle Mariners are -1.5 +125 run line favorites at BetMGM, while the Houston Astros are +1.5 -148 run line underdogs at BetRivers.
MLB Odds Example
| Game |
 BetMGMBet |
|---|---|
|
Mariners
Astros
7:10pm CDT
|
-135+115 |
- Houston Astros bettors risk $100 to win $115 at +115 odds. The implied probability for Houston Astros is 46.51%.
- Seattle Mariners bettors risk $100 to win $74.07 at -135 odds. The implied probability for Seattle Mariners is 57.45%.
Seattle Mariners at Houston Astros Prop Bets
|
BetMGM Bet |
|
|---|---|
|
Mariners
Astros
First Team to Score
7:10pm CDT
|
-175+135Bet |
|
Mariners
Astros
Tie
1st Inning Winner
7:10pm CDT
|
+270+340-140Bet |
|
Mariners
Astros
Tie
First 3 Innings Winner
7:10pm CDT
|
+125+165+280Bet |
|
Mariners
Astros
To Extra Innings
7:10pm CDT
|
Yes +775No -1400Bet |
|
BetMGM |
|
|
Mariners
Astros
1st Team to Score Will Win
7:10pm CDT
|
Yes -250No +190Bet |
|
Astros
Total Runs
SEA at HOU 7:10pm CDT |
3.5 o -1403.5 u +105Bet |
|
Mariners
Total Runs
SEA at HOU 7:10pm CDT |
4.5 o -1104.5 u -118Bet |
|
George Kirby
Strikeouts Thrown
SEA at HOU 7:10pm CDT |
4.5 o +1304.5 u -165Bet |
|
BetMGM |
|
|
Lance McCullers Jr
Strikeouts Thrown
SEA at HOU 7:10pm CDT |
4.5 o -1104.5 u -115Bet |
Seattle Mariners & Houston Astros Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Seattle Mariners World Series Odds| Team |
BetMGM |
 BetRivers |
|---|---|---|
| Mariners | +1800 Bet |
+2000 Bet |
| Team |
BetMGM |
BetRivers |
|---|---|---|
| Astros | +2500 Bet |
+2000 Bet |
Seattle Mariners & Houston Astros Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Seattle Mariners | 28 | 20 | 0.583 | +4.0 | 13-11 | 15-9 | 227 | 200 | +27 | W1 | 6-4 |
| Houston Astros | 25 | 24 | 0.510 | +7.5 | 15-9 | 10-15 | 195 | 179 | +16 | L2 | 5-5 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Seattle Mariners vs Houston Astros MLB Game
- Open a new sports betting before game time.
Review our list of sports betting sites. Open a new before the game starts on Thursday, May 22nd, 2025 at 7:10 pm CDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
- Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Paypal.
- Tap to the sportsbook's MLB page, look for the Seattle Mariners vs Houston Astros Game.
Navigate to the sportsbook's MLB page. Next, look for live or matchups. Select the Seattle Mariners vs Houston Astros Game.
- Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your balance after the game.
Other May 22, 2025 MLB Games
- Texas Rangers vs New York Yankees - 11:35am CDT
- San Diego Padres vs Toronto Blue Jays - 12:05pm CDT
- Philadelphia Phillies vs Colorado Rockies - 2:10pm CDT
- Los Angeles Angels vs Oakland Athletics - 2:35pm CDT
- Cleveland Guardians vs Detroit Tigers - 5:40pm CDT
- Milwaukee Brewers vs Pittsburgh Pirates - 5:40pm CDT
- Baltimore Orioles vs Boston Red Sox - 5:45pm CDT
- Atlanta Braves vs Washington Nationals - 5:45pm CDT