The Orioles will play the Brewers on Wednesday, May 21st, 2025. Your timezone's first pitch time is 12:10 pm CDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Baltimore Orioles have a 82.00 power ranking. The power ranking for the Milwaukee Brewers is 89.67.
- Visiting Baltimore Orioles - The Baltimore Orioles have a 7-16 record as a visiting team, ranking them 8th Overall for visiting team wins.
- Home Milwaukee Brewers - The Milwaukee Brewers have a 14-9 record as a home team. They rank 4th for home team wins in the Overall standings.
- Runs Scored - The Baltimore Orioles currently stand 22nd (173) Overall, with the Milwaukee Brewers ranking 13th (203) for runs scored.
- Runs Allowed - The Baltimore Orioles are 4th (259) Overall for runs allowed. The Milwaukee Brewers stand 12th (209) for runs allowed.
- Team Streaks - The Baltimore Orioles have lost their last 7 games. Meanwhile, the Milwaukee Brewers have won their last 2 games.
- Team Records - The Baltimore Orioles have a 15-31 Overall record (12.0 GB American East Division), with the Milwaukee Brewers possessing a 23-25 Overall standing (5.0 GB National Central Division).
Captain Shady Lines
A broken com is right at least twice a day.
Avast, ye scallywags! The Orioles be settin' sail for Milwaukee on Wednesday...
They be havin' a dismal record, winnin' only 15 outta 46 games played...
The Brewers may be favored, but don't count out the Orioles just yet...
Ye best be headin' over to SportsBetting3.com to bet on this game...
Review the odds below and place yer bets wisely, me hearties...arrrr!
Best Orioles at Brewers Odds
| Underdog Baltimore Orioles |
Favorite Milwaukee Brewers |
|---|---|
| Over | Under |
|---|---|
| Underdog Milwaukee Brewers |
Favorite Baltimore Orioles |
|---|---|
Matchup Odds FAQs
The Milwaukee Brewers are the -115 moneyline favorite at BetMGM and the Baltimore Orioles are the +100 moneyline underdog at BetRivers.
The best over line is 8 -127 runs at BetRivers, which means you risk $127 to win $100 betting the over. The best under line is 8.5 -110 runs at BetMGM, and that means you risk $110 to win $100 betting the under.
The Baltimore Orioles are +1.5 -230 run line favorites at BetRivers, while the Milwaukee Brewers are +1.5 -190 run line underdogs at BetMGM.
MLB Odds Example
| Game |
 BetMGMBet |
|---|---|
|
Orioles
Brewers
5/21/25 12:10pm CDT
|
-105-115 |
- Baltimore Orioles bettors risk $100 to win $95.24 at -105 odds. The implied probability for Baltimore Orioles is 51.22%.
- Milwaukee Brewers bettors risk $100 to win $86.96 at -115 odds. The implied probability for Milwaukee Brewers is 53.49%.
Baltimore Orioles at Milwaukee Brewers Prop Bets
|
BetMGM Bet |
|
|---|---|
|
Orioles
Brewers
First Team to Score
5/21/25 12:10pm CDT
|
-150+118Bet |
|
Orioles
Brewers
Tie
1st Inning Winner
5/21/25 12:10pm CDT
|
+300+275-130Bet |
|
Orioles
Brewers
Tie
First 3 Innings Winner
5/21/25 12:10pm CDT
|
+150+130+300Bet |
|
Orioles
Brewers
To Extra Innings
5/21/25 12:10pm CDT
|
Yes +775No -1400Bet |
|
BetMGM |
|
|
Orioles
Brewers
1st Team to Score Will Win
5/21/25 12:10pm CDT
|
Yes -250No +190Bet |
|
Orioles
Total Runs
BAL at MIL 5/21/25 12:10pm CDT |
4.5 o +1104.5 u -145Bet |
|
Brewers
Total Runs
BAL at MIL 5/21/25 12:10pm CDT |
3.5 o -1503.5 u +115Bet |
|
Chad Patrick
Strikeouts Thrown
BAL at MIL 5/21/25 12:10pm CDT |
4.5 o -1204.5 u -105Bet |
|
BetMGM |
|
|
Tomoyuki Sugano
Strikeouts Thrown
BAL at MIL 5/21/25 12:10pm CDT |
3.5 o -1253.5 u -105Bet |
Baltimore Orioles & Milwaukee Brewers Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Baltimore Orioles World Series Odds| Team |
BetMGM |
 BetRivers |
|---|---|---|
| Orioles | +10000 Bet |
+3500 Bet |
| Team |
BetMGM |
BetRivers |
|---|---|---|
| Brewers | +10000 Bet |
+7000 Bet |
Baltimore Orioles & Milwaukee Brewers Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Milwaukee Brewers | 24 | 26 | 0.480 | +8.5 | 15-10 | 9-16 | 212 | 219 | -7 | L1 | 5-5 |
| Baltimore Orioles | 16 | 32 | 0.333 | +15.5 | 8-15 | 8-17 | 183 | 268 | -85 | W1 | 2-8 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Baltimore Orioles vs Milwaukee Brewers MLB Game
- Open a new sports betting before game time.
Review our list of sports betting sites. Open a new before the game starts on Wednesday, May 21st, 2025 at 12:10 pm CDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
- Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Paypal.
- Tap to the sportsbook's MLB page, look for the Baltimore Orioles vs Milwaukee Brewers Game.
Navigate to the sportsbook's MLB page. Next, look for live or matchups. Select the Baltimore Orioles vs Milwaukee Brewers Game.
- Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your balance after the game.
Other May 21, 2025 MLB Games
- Cincinnati Reds vs Pittsburgh Pirates - 5/21/25 11:35am CDT
- Chicago Cubs vs Miami Marlins - 5/21/25 12:10pm CDT
- Houston Astros vs Tampa Bay Rays - 5/21/25 12:10pm CDT
- Detroit Tigers vs St. Louis Cardinals - 5/21/25 12:15pm CDT
- Seattle Mariners vs Chicago White Sox - 5/21/25 1:10pm CDT
- Cleveland Guardians vs Minnesota Twins - 5/21/25 2:30pm CDT
- Kansas City Royals vs San Francisco Giants - 5/21/25 2:45pm CDT
- New York Mets vs Boston Red Sox - 5/21/25 5:45pm CDT
- Atlanta Braves vs Washington Nationals - 5/21/25 5:45pm CDT
- Texas Rangers vs New York Yankees - 5/21/25 6:05pm CDT
- San Diego Padres vs Toronto Blue Jays - 5/21/25 6:07pm CDT
- Cleveland Guardians vs Minnesota Twins - 5/21/25 6:10pm CDT
- Philadelphia Phillies vs Colorado Rockies - 5/21/25 7:40pm CDT
- Los Angeles Angels vs Oakland Athletics - 5/21/25 9:05pm CDT
- Arizona Diamondbacks vs Los Angeles Dodgers - 5/21/25 9:10pm CDT