New York Mets vs Boston Red Sox Odds

The Mets will play the Red Sox on Wednesday, May 21st, 2025. Your timezone's first pitch time is 5:45 pm CDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


Bonus
REVIEW PA *New* Customers - Bet $10, Get $150 in Bonus Bets If You Win
Thru 6/2/2025 - Bonus Bets Expire in 7 Days
One new customer offer/Add'l

Bet Now
21+ Playable in PA only
Gambling Problem? Call 1-800-GAMBLER
REVIEW New Customers - 2nd Chance Bet up to $500 - Code: SPORTS
Bet Now
21+ Playable in PA only
Gambling Problem? Call 1-800-GAMBLER

Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - As the 2025 season continues, the New York Mets possess a 96.00 SportsBetting3.com power ranking. The Boston Red Sox now have a 93.00 power ranking. Teams with a higher SportsBetting3.com power ranking will typically be moneyline favorites.
  • Visiting New York Mets - The New York Mets head into this matchup with a 12-15 record as a visiting team. This standing ranks them 3rd Overall for visiting team wins.
  • Home Boston Red Sox - The Boston Red Sox will throw the first pitch possessing a 14-11 home team record. That puts them 4th for home team wins in the Overall MLB standings.
  • Runs Scored - New York Mets batters have produced 213 runs, ranking them 12th Overall, with the Boston Red Sox ranking 6th (239) for runs scored.
  • Runs Allowed - New York Mets pitchers and fielders have allowed 161 runs, ranking them 25th Overall for runs allowed. Meanwhile, the Boston Red Sox now rank 7th Overall, allowing 227 runs.
  • Team Streaks - The New York Mets have lost their last 3 games. Their opponent, the Boston Red Sox have won their last 2 games.
  • Team Records - Let's review each team's records. The New York Mets have a 29-20 Overall record (1.5 GB National East Division), with the Boston Red Sox notching a 25-25 Overall standing (4.5 GB American East Division).

Captain Shady Lines

A broken com is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye scallywags! The Mets be facin' off against the Red Sox...

Ye Mets be comin' in strong with a winnin' record, but barely holdin' on...

The Red Sox may be at home, but they be middlin' at best...

This be one match ye won't want to miss, so bet on it...

Check out this game's prop bets below and place yer wagers...

(But , always gamble responsibly, ya hear?)...

Review each team's standing at the bottom of the page, and may the best team win!

Best Mets at Red Sox Odds


Best Moneyline Betting Odds
Underdog

New York Mets
Favorite

Boston Red Sox
The Boston Red Sox are the -150 moneyline favorite. Risk $150 to win $100 on the Boston Red Sox at how to bet on money lines.

Best Total Betting Odds
Over Under
total bets.

Best Run Line Betting Odds
Underdog

New York Mets
Favorite

Boston Red Sox
The Boston Red Sox have a -1.5 +150 run line at how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the New York Mets vs Boston Red Sox MLB game on Wednesday, May 21st, 2025?

The Boston Red Sox are the -150 moneyline favorite at BetMGM and the New York Mets are the +128 moneyline underdog at BetRivers.

What is the over-under total line for the New York Mets vs Boston Red Sox MLB game on Wednesday, May 21st, 2025?

The best over line is 7.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the New York Mets vs Boston Red Sox MLB game on Wednesday, May 21st, 2025?

The Boston Red Sox are -1.5 +150 run line favorites at BetMGM, while the New York Mets are +1.5 -175 run line underdogs at BetRivers.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Mets
Red Sox
5/21/25 5:45pm CDT
+125-150
Bet $100 at BetMGM Pennsylvania
21+ Playable in PA only
Gambling Problem? Call 1-800-GAMBLER
Possible Moneyline Outcomes
  • New York Mets bettors risk $100 to win $125 at +125 odds. The implied probability for New York Mets is 44.44%.
  • Boston Red Sox bettors risk $100 to win $66.67 at -150 odds. The implied probability for Boston Red Sox is 60%.

New York Mets at Boston Red Sox Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Mets
Red Sox
First Team to Score
5/21/25 5:45pm CDT
-120-105Bet
Mets
Red Sox
Tie
1st Inning Winner
5/21/25 5:45pm CDT
+375+290-160Bet
Mets
Red Sox
Tie
First 3 Innings Winner
5/21/25 5:45pm CDT
+195+120+240Bet
Mets
Red Sox
To Extra Innings
5/21/25 5:45pm CDT
Yes +700No -1100Bet
BetMGM Sports Betting BetMGM
Mets
Red Sox
1st Team to Score Will Win
5/21/25 5:45pm CDT
Yes -250No +190Bet
Red Sox
Total Runs
NYM at BOS
5/21/25 5:45pm CDT
3.5 o -1453.5 u +110Bet
Mets
Total Runs
NYM at BOS
5/21/25 5:45pm CDT
3.5 o +1003.5 u -130Bet
Garrett Crochet
Strikeouts Thrown
NYM at BOS
5/21/25 5:45pm CDT
7.5 o +1107.5 u -145Bet
BetMGM Sports Betting BetMGM
Tylor Megill
Strikeouts Thrown
NYM at BOS
5/21/25 5:45pm CDT
5.5 o -1455.5 u +110Bet

New York Mets & Boston Red Sox Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

New York Mets World Series Odds
2025 New York Mets World Series Odds

Team
BetMGM Sports Betting BetMGM BetRivers Sports Betting BetRivers
Mets
+900
Bet
+1000
Bet
Boston Red Sox World Series Odds
2025 Boston Red Sox World Series Odds

Team
BetMGM Sports Betting BetMGM BetRivers Sports Betting BetRivers
Red Sox
+2500
Bet
+2000
Bet

New York Mets & Boston Red Sox Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - New York Mets, Boston Red Sox
Team W L Pct GB Home Away RS RA Diff Strk L10
New York Mets 29 20 0.592 +3.5 17-5 12-15 213 161 +52 L3 4-6
Boston Red Sox 25 25 0.500 +8.0 14-11 11-14 239 227 +12 W2 5-5

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the New York Mets vs Boston Red Sox MLB Game

  1. Open a new sports betting before game time.

    Review our list of sports betting sites. Open a new before the game starts on Wednesday, May 21st, 2025 at 5:45 pm CDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Paypal.

  3. Tap to the sportsbook's MLB page, look for the New York Mets vs Boston Red Sox Game.

    Navigate to the sportsbook's MLB page. Next, look for live or matchups. Select the New York Mets vs Boston Red Sox Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your balance after the game.

Other May 21, 2025 MLB Games

Odds Preview 12676